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Semaglutide for Diabetes, Type 2 User Reviews (Page 2)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 6.3 out of 10 from a total of 1082 reviews for the treatment of Diabetes, Type 2. 49% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Semaglutide

  • Shebee
  • Taken for 1 to 6 months
  • September 4, 2020

Ozempic (semaglutide) "I've been on Ozempic for 8 weeks. At first, I had side effects of a lot of nausea. Now, I wake up cold and clammy the last week and very anxious. Overall feeling unwell. Wondering if anyone else has experienced this?"

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  • Brenlee
  • Taken for 1 to 6 months
  • May 26, 2024

Ozempic (semaglutide) "Started with the 0.25 dose & after 5 weeks went to 0.50. Side effects were minimal, mostly just an upset stomach for the first day after a shot. Pens were easy to use & directions easy to follow. My A1c went from 10.3 to 6.2 after 90 days & I lost 22 lbs. I made significant dietary changes, which were helped because overeating gave me that 'too full to move' feeling you get on Thanksgiving, even with small portions. I eat 4-5 times a day but in small portions & calories under 1200 daily. Constipation was avoided by an increase in fiber/vegetables and water."

10 / 10
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  • Chris
  • Taken for 1 to 6 months
  • July 11, 2021

Ozempic (semaglutide) "I suffered from - Loss of appetite - Exhaustion - Nausea - Vomiting (once a week, usually 2 days after my injection) - Low blood sugar events (probably caused because I just had no appetite). When I spoke to my pharmacist, she encouraged me to try to hang in there, telling me it would get better, and it finally has. I was not expecting it to take over 3 months though. My readings are all good, and I've lost 28 lbs, so there were benefits to sticking it out, but it was hard. I had decided that I would continue to take the medication until my next appointment, and if things were still bad, I would tell the doctor that I no longer wanted to use it. Things are better, and my appointment is next week."

5 / 10
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Frequently asked questions

  • Lem
  • Taken for 1 to 6 months
  • February 1, 2021

Ozempic (semaglutide) "Honestly, I am so impressed so far with these meds. My weight had been creeping up due to insulin resistance (which itself makes it harder to lose weight) and PCOS. My doctor recommended I try this in conjunction with a very low carb and calorie diet. I started with a half dose of 0.25mg once a week injection and then after 2 weeks up to 0.5mg a week. So far in 6 weeks, I’ve lost 15cm from my waist and 9cm off my hips, and 5cm off my bust. I have been eating light and easy, roughly 1000 calories a day. Haven’t weighed myself yet as I’d prefer to see the difference in cm. This medication makes me feel a little nauseous the first day or two after my shot, but after that, I never feel hungry. I can quite easily eat a super small portion and feel full! I drink about 2L of water a day and do about 8000 steps at my job. It really has been great and so much cheaper than Saxenda, which was another one I was considering. Hopefully, I continue to lose weight!"

10 / 10
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  • leila...
  • May 19, 2021

Ozempic (semaglutide) "I've been on it for 7 weeks. I have had the runs as others have noted, and the sour stomach, but what I also noted is that those symptoms are worse if you've eaten too much or a heavier meal before bedtime. Small snacks are ok. I don't drink any sugar-laden beverages, and I eat lots of fiber already. My diet is mostly vegetarian, but not for any reason other than my stomach just feels better on it. I think that has helped keep the side effects in check. So far, I've lost 8 lbs, which TBH is kind of shocking. I never thought my body would give up this weight, but I'm heading in the right direction. Sugars are dropping nicely, especially my fasting sugar. I have that hypo drop and spike when you wake up, and that seems to be leveling off, which is great. So I'm going to keep going. Oh, and I didn't jump in with dosing, I started with 0.25 and kept on that for six weeks and only just now moving to 0.5. Slow gradual is the right way. Too much at once will make you sick."

9 / 10
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Are you taking this medicine?

  • Amanda
  • Taken for 6 months to 1 year
  • December 16, 2021

Ozempic (semaglutide) "Listen to me, Ozempic will change your life, but you cannot eat synthetic sugar at all. I had severe Hashimoto's, PCOS, insulin resistance, and severe diabetes symptoms. HbA1c was high, all cholesterols were high despite the healthiest of diets. My numbers cleared from severe to perfect in 1 month! I had full-body swelling, severely cracked ankles, swollen feet, neck, legs, major hair loss... a nightmare. I began taking Ozempic. I was very sick. It made me extremely nauseous. I got severe diarrhea, but let me tell you, I lost 17 pounds of water weight in one month. My doctor couldn’t believe it. In four months, I lost 40 lbs. The nausea was mild to severe the entire time, but the results were borderline insane. It reset my metabolism, took all of the inflammation away from my joints, neck, back, my feet completely healed within one month. It’s barely believable. I spent two months on 0.25 and increased to 0.5 once a week for ten more months. High praise!"

10 / 10
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  • Const...
  • Taken for less than 1 month
  • March 26, 2023

Rybelsus (semaglutide) "I took 3 mg of Rybelsus for about two weeks. I noticed right away that I was not able to poop normally. I thought constipation would resolve naturally since I don’t have issues with it normally. Now, I’ve been off of it for a week and I’ve had two ER visits because I can’t poop. I also struggle to pee because the thought is the backed-up poop is pressing on things it shouldn’t. Had to have a catheter drain me out. I did a week of Miralax, two days of Dulcolax, one ER cocktail, and an enema, and none of it has helped. At this point, I’m scared it will take surgery to remove the poop. If you’re taking this medicine please stay in tune with your body and mitigate early if you’re starting to experience any constipation."

1 / 10
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More FAQ

  • Dnw
  • Taken for 6 months to 1 year
  • August 30, 2020

Ozempic (semaglutide) "I’ve been on Ozempic for 6 months. I had gestational diabetes with both children so I know I have an increased risk of type 2. I had bloodwork done and unsurprisingly my fasting sugar was high, but my A1C was high normal. My doctor prescribed Ozempic and I am currently at 1mg/week. Results: blood sugar in perfect range, lost 20 pounds (15% body weight), loss of sense of taste for tons of foods, alcohol aversion. All in all, I’m far healthier but I do miss enjoying food. I wonder if this is sustainable long term. Time will tell."

10 / 10
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  • joe...
  • November 20, 2020

Rybelsus (semaglutide) "I first took the 3mg dose for 30 days. I had no side effects, and it is really controlling my appetite. Now I am on 7mg. So far, my weight was 242. I have been on Rybelsus for about 4 months, and my weight now is 215. I'm hoping to lose more. No side effects, feel better, light food craving. I hope to stay on this for 4 more months. Thanks Rybelsus. Joe C."

9 / 10
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  • Kristy
  • Taken for less than 1 month
  • August 23, 2018

Ozempic (semaglutide) "I have been on Ozempic for 2.5 weeks now and I have lost 12 pounds. I don’t eat anything fried or greasy. I watch fat intake because this medicine can make you sick if you have too much fat in what you are eating. It can also make you sick if you overeat. If you eat small to moderate meals with light snacks in between, you will probably not have any problems. If you cannot stay away from fast food and greasy pizza, you will have a problem. I have found that this medicine makes me not as hungry. It takes the edge off. It also keeps me from craving junk. I get full at mealtime, eating less. I drink a lot of water too. I also use an app on my phone to log food, calories, and exercise. I weigh once a week. I hope this helps someone else that is considering this drug."

10 / 10
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  • Jeny
  • November 29, 2020

Rybelsus (semaglutide) "My doctor put me on Rybelsus in March/April 2020. I will admit the nausea was pretty bad for about the first month, but I stuck to it because it was really working well on my blood sugar. Since I started, I have lost 42 lbs! I have not been dieting, but I do have some outdoor projects that required physical labor, like shoveling dirt, clearing brush, moving stones, etc. The nausea only comes back when my sugar is low and I really need to eat. I don’t even get a growling stomach anymore. I would recommend Rybelsus to anyone looking to manage their blood sugar and lose some weight."

10 / 10
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  • Amie
  • Taken for less than 1 month
  • February 13, 2022

Rybelsus (semaglutide) "I was very frightened after reading the reviews. I am 52 and had gained from 130 pounds to 158, the most I have ever weighed in my life. Started the 3mg 3 weeks ago and have lost 10 pounds with no side effects other than occasional slight nausea. My appetite has decreased but for the better. I am walking 3 miles a day and eating very healthy. Stopped drinking soda, now only flavored water. I consider this a miracle. Never lost weight this quickly. Happy as heck. Will continue the 3 mg and recheck A1C. So far this rocks. If it enables me to get in control of my eating and lose to a healthy weight to better my overall health, then I call it a huge success. Love, love, love it!"

10 / 10
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  • AKAgirl
  • Taken for less than 1 month
  • January 26, 2021

Ozempic (semaglutide) "I have tried them all! I was diagnosed with diabetes at the age of 18, and I will be 40 this September. When I say I have tried them all, it’s no exaggeration, but my search stops here! This medicine has done in a couple of weeks what I have been trying to do all my adult life! My blood sugar is perfect! I actually look forward to testing my sugars throughout the day. The other day, I cheated and had a slice of caramel cheesecake. Normally, this would spike my blood sugars well over 250, but when I tested my sugar one hour after consumption, I was at 132! It only got lower as the night went on! This is some good stuff! I am so happy my doctor recommended this for me! I’m in love! I’m finally optimistic about my future with this dreadful disease."

10 / 10
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  • Skis
  • Taken for 1 to 6 months
  • May 31, 2020

Ozempic (semaglutide) "My husband began taking Ozempic for his Type 2 diabetes several months ago and experienced minimal unpleasant side effects. His food consumption is down approximately 2/3 (no more 'first breakfast and second breakfast' and 'first dinner and second dinner') and he has been able to reduce his diabetes medications. He has been steadily losing excess weight. A bonus is the chronic loose stools he used to suffer have been eliminated. I started taking Ozempic for my Type 2 diabetes 6 weeks ago. My food consumption is down significantly and I've been able to discontinue all other diabetes medications. I've had some slight nausea and a mild bit of constipation, both of which have been easily alleviated through dietary changes (much smaller meals, more fiber and more spicy food). We absolutely love this medication."

10 / 10
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  • dsgrey
  • Taken for 1 to 2 years
  • August 24, 2020

Ozempic (semaglutide) "I've been using Ozempic for 18 months. A1c has dropped from 8.1 to 6.0. Weight dropped from 195 lbs to 157 lbs. Minor side effects for the first two weeks. I dropped most of the weight within 4 months and my A1c went down to 6.3 in those 4 months. My doctor decided to take me off Ozempic after 6 months to see if I'd stabilized, but within 4 weeks, my A1c was back in the upper 7s. I'm staying on Ozempic for now. Great medication but a ridiculous price."

10 / 10
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  • Cando
  • Taken for 1 to 6 months
  • November 29, 2020

Rybelsus (semaglutide) "When I first started the 3mg of Rybelsus, the nausea for the first 3 weeks was nearly unbearable. However, like magic, around day 21, it stopped. I don’t feel as full as I did at the beginning now that I’m starting my second month of 7mg. However, I continue to lose weight with diet and exercise. If you’re struggling at the beginning - hold on for 30 days - it might pass like it did for me!"

9 / 10
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  • MidNi...
  • August 21, 2020

Ozempic (semaglutide) "My health wasn't good, so I fired the nurse practitioner I was seeing and got an internist doctor. Found out my thyroid was almost non-functional, high blood pressure, and my pre-diabetes rate was on a serious climb. 1 year later, I was at the right dose of Synthroid. Doctor put me on metformin and phentermine, and added Ozempic 2 weeks later at 0.25. That was a rough ride; I was nauseated and dizzy a lot! I started at 265 lbs, and every day I would see a pound or 2 come off. As of this morning, I weighed in at 239, and I'm up to 1 mg dose of Ozempic weekly. I take the anti-nausea now just before my Ozempic dose, and that's it. I use doTERRA ginger. A1C down to 5! I'm glad I listened to my doctor and my pharmacist and stuck with it. Anything worth having doesn't usually come easy! I would like to get down to the 160-170 range; I'm 5'11'', and thinner than that, I start to look like Olive Oyl! OH Popeye!"

10 / 10
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  • Nw272...
  • Taken for 1 to 6 months
  • June 20, 2021

Ozempic (semaglutide) "Started April 1, 2021, on Ozempic low dose. 3-week intervals it was increased. Side effects were constipation (went on laxatives to help), pain in my back (severe), bloating. Week 11 increased to 1mg, the side effects were major bloating, diarrhea, sounds in my stomach (crazy), nauseous, feeling under the weather. My appetite has decreased to the point that I only eat 2 meals a day that are small. My sugar levels have decreased from 7.1 to 5.2 A1C. I’ve noticed that I have been kept awake some nights like I’m nervous for some reason. In the first 3 weeks, I’ve lost 15 pounds. Haven’t checked since I want to wait but can feel a difference. The pains in the stomach are really uncomfortable, and the bloating I will try gas-x for relief. When I try to eat more than I should, my body tells me that I’m full. If I go beyond that point, I get severe pains in the stomach for hours. But depends on what I eat. Going to stay with smaller portions/healthier foods."

8 / 10
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  • Janny
  • Taken for 1 to 6 months
  • March 15, 2021

Ozempic (semaglutide) "My doctor gave me Ozempic 0.5 to start with. I always had upset stomach, diarrhea with most foods, and an overall sick feeling all the time. I was able to 'live' with it until now. She decided to up my dose to the 1.0 and my body went into total chaos. I am always nauseous, constipated, got reflux, feels like my food is stuck in my stomach and doesn't go anywhere. I'm constantly burping and feeling bloated. The sick feeling feels intensified and I cannot function at work. I took my last one this past Friday night and was miserable all weekend long. Today I am at work unable to function at my best because the nausea is bad. I would say it is effective in lowering your blood sugar numbers and helping you lose weight but not worth feeling horribly sick over. I will not be using this medication any longer."

5 / 10
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  • Dori
  • Taken for 1 to 6 months
  • December 21, 2020

Rybelsus (semaglutide) "I started taking Rybelsus 3mg. I was nauseous at first and constipated. I was also belching a lot. After 2 weeks, that seemed to stop. I've been on the 7mg for 17 days and the nausea, indigestion, stomach pain, and now diarrhea have been almost unbearable and are getting worse. I've also started feeling panicky and anxious in the middle of the night with rapid heartbeat. I'm stopping the 7mg tomorrow and calling my doctor. I can't feel like this at Christmas. Going to see if she will put me back on 3mg. My A1C was 9.0. I have no idea what it is now. I've also lost 18 lbs because I can barely eat anything. This isn't worth it."

3 / 10
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  • Saidie
  • October 17, 2020

Rybelsus (semaglutide) "Dr. ordered 3mg 30 days ago to be added to Metformin 2000mg. Blood sugars have decreased from a range of 200-350 to 120-150. Weight reduced by 14 pounds. I experienced nausea and fullness for the first two weeks. That has tapered off but appetite suppression has continued. After a month, the doctor is pleased with the results, as am I. He has ordered me to continue on the 3mg and my insurance has agreed to cover it with a copay I can afford. I am so grateful for this new med!"

10 / 10
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  • Anon...
  • February 26, 2022

Ozempic (semaglutide) "Reading many of the reviews frightened me so I thought it was important to share my positive experience. I’ll first say, I’m horrified of needles. However, you can’t feel the needle at all, the medication going in sort of burns a bit, but that’s it! I’ve been on Ozempic for 5 months. I started at 254 lbs and started taking 0.25mg for 6 weeks. No side effects in the slightest. I also didn’t lose much either though because it is your body getting used to the medication rather than fixing your blood sugars. I then moved up to 0.5 and started seeing results with my weight and still no bad side effects other than eating less. I recently moved up to 1mg and am now down a total of 45 pounds in 5 months. Still no bad side effects. Eating has to be much more mechanical though because my hunger cues aren’t as strong, but no nausea. I would highly recommend this drug! Ps inject in your thighs, I believe this is the reason I’ve had no bad side effects my entire journey!"

10 / 10
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  • Laulau
  • Taken for 1 to 6 months
  • October 13, 2019

Ozempic (semaglutide) "I've been on ozempic about 4 weeks now. Started at 0.25 now onto O.5mg. The only mild side effect I have is the sulphur burps other than that I don't really have any. The odd sick feeling but it's not too strong of a feeling. This medication has cut the sugar cravings in half to non existent therefore have lost bit of weight which is noticeable. Food habits now are also none existant. I feel fuller for longer. This drug is amazing and to only Inject once weekly is fab! I do recommend ozempic highly. I Held a lot of weight around my stomach to which now its starting to shift. To me it's been a lifechanger and I hope to anyone considering reaps the same experience from myself on it. Gl x"

10 / 10
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  • Calez...
  • Taken for 1 to 6 months
  • September 21, 2019

Ozempic (semaglutide) "Since starting Ozempic, all my numbers have gotten considerably better. I did have nausea for several months, but I took medicine to counteract the nausea, and now I’m feeling much better. My appetite has been cut in half. I have lost a total of 40 lbs so far, and I couldn’t tell you the amount of inches I have lost; it seems that I lost inches first and then weight. I have started going to the gym. My advice to anyone starting Ozempic is to stop eating as soon as you get that first feeling of being full; don’t try to finish the plate just because you don’t want to waste food because it will make you sick if you force yourself to eat it all."

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  • joano
  • Taken for 1 to 6 months
  • August 15, 2020

Rybelsus (semaglutide) "Dr put me on Rybelsus since I had bad luck with Trulicity and feeling sick every time I took the shot. The first month of the dose 3mg, I noticed I never ate. I had a complete lack of appetite. I was exhausted, had weird dreams, and a constant feeling of anxiety, and sometimes insomnia. I put up with it. The second round with the 7 mg, the first day I was sicker than heck. I felt like I was on a cliff dangling, my anxiety turned into panic, rapid heartbeat, and I was unable to sleep. I stopped after day 4. I called the doctor but she never got back to me. I am debating trying to take 7mg every other day or go back to the 3mg and see if there is a difference now that it is almost out of my system. It is brutal to the body. The warnings say nothing about the feelings of anxiety or the insomnia."

3 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.