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Semaglutide for Diabetes, Type 2 User Reviews (Page 3)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 6.3 out of 10 from a total of 1082 reviews for the treatment of Diabetes, Type 2. 49% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Semaglutide

  • Kay
  • Taken for 1 to 6 months
  • August 16, 2020

Ozempic (semaglutide) "With an A1C approaching 11, it was time to try something else in addition to Novolog and Tresiba, so my doctor added Ozempic. I also quit all alcohol and became a vegetarian. The first 3 weeks at 0.25 left me with a decreased appetite, nothing severe. The pounds started dropping off; fast forward 3 months and I am 22 lbs lighter. I love Ozempic, no bad side effects, and my insulin needs have decreased (not gone away); best of all, my A1C was 7! A lifestyle change helped a lot, but I credit Ozempic for many of these positive changes."

10 / 10
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  • CADoc...
  • Taken for 1 to 6 months
  • December 13, 2020

Rybelsus (semaglutide) "I’m prediabetic, HbA1c 5.7. And I’ve been struggling to lose weight for 20 years. I have an excellent diet, but I eat too much. I’m hungry all the time. I started Rybelsus (paying out of pocket - Ouch) to see if it’s worth hassling my insurance company. On 3 mg, I felt nothing - no nausea, but experienced loose stools. When I went to 7 mg, I felt nausea for 1 hour after taking the pill and decreased appetite the rest of the day. I am easily staying on my 1400-1500 calorie diet, which has never been easy for me in the past. At 1 month of 7 mg, I’ve lost 8 pounds (255 to 247) and feel very encouraged. The science behind this medicine is inspiring."

10 / 10
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  • Happy
  • Taken for 1 to 6 months
  • June 10, 2020

Ozempic (semaglutide) "I've been using this off-label for weight loss for 3 months after consistent diet and exercise, and allegedly controlled Hashimoto's left me frustrated that I still couldn't lose weight. This drug has been amazing. I do still suffer from occasional headaches that are moderate to severe, and if I eat something I 'shouldn't,' there are usually digestive repercussions. But I'm down 15+ pounds in 3 months without any real change to my prior (very good) lifestyle. I lean into the days I'm not hungry and allow myself to eat on the days that I am. It is expensive, but there are great coupons. I will stay at the 0.5 dose until I reach my goal weight and then try to taper off."

10 / 10
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Frequently asked questions

  • SHano
  • Taken for less than 1 month
  • February 2, 2021

Ozempic (semaglutide) "I feel that the best practice for this medicine would be to take about only 8-10 clicks (17 clicks = 0.25) for the first several weeks and then build yourself up to the full 0.25 dose. That way you can see what side effects you are going to experience and if they are tolerable of not. I took 0.25 and suffered from severe diarrhea for almost the full 7 days. Ended up in the hospital for the last 4 days until the side effects wore off. The only positive, was that I lost almost 20lbs. I would be very careful taking this medicine."

1 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • May 26, 2024

Ozempic (semaglutide) "Ozempic is a godsend! It lowered my sugar considerably, to the point that I had to lower my Trulicity. I have lost weight, about 15 lbs. But the biggest thing is, I am an alcoholic and have cirrhosis, but was still drinking my two glasses of wine every night. After being on this wonder drug for 6 months I suddenly had no craving for alcohol! A miracle! Thanks to all who made this possible!"

10 / 10
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Are you taking this medicine?

  • Type...
  • Taken for less than 1 month
  • April 26, 2023

Rybelsus (semaglutide) "I have been taking 3mg Rybelsus for 14 days for type 2 diabetes alongside Metformin. I have had no negative side effects from this medication other than a low blood sugar reading most days. I take it around 6 am with a small amount of water as directed and then breakfast around an hour later. I have lost 14 lb in weight but I have started eating very healthy with a low carb intake. My appetite has reduced and my portion sizes have reduced as I do feel much fuller for longer. So far so good."

10 / 10
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  • Sarah
  • Taken for 1 to 6 months
  • April 7, 2020

Ozempic (semaglutide) "Do not take this medication! After injecting the .5 mg dosage for two months, I began to have digestive issues. My doctor sent me for medical tests and found that I developed Pancreatitis. I was told to stop using Ozempic immediately!"

1 / 10
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More FAQ

  • Ron
  • Taken for 6 months to 1 year
  • September 8, 2019

Ozempic (semaglutide) "I’ve been taking Ozempic for eight months. I’ve had minimal side effects on a 0.5mg dose. I’m taking this for weight loss with Metformin and a low-carb diet. I’ve lost 70 pounds from 265 lbs to 195 lbs. The change in my health has been remarkable. I call it the wonder drug."

10 / 10
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  • siva
  • Taken for 1 to 6 months
  • December 10, 2020

Rybelsus (semaglutide) "My dr. put me on Rybelsus as I had high blood sugar. I had too much difficulty taking the 3 mg with nausea, diarrhea, and Headache. I planned to quit but I read the reviews here. I somehow managed my symptoms and tried harder. My dr. then increased dosage to 7 mg. Rybelsus was able to bring my blood sugar levels from 10.6 to 5.6 almost normal levels in a period of 3 months. If anyone planning to quit please persevere and the results are amazing. It practically stops your cravings for food and helps you stabilize. Another miracle was that I was finally able to quit coffee in the morning as I get migraine without it. Compared to the nausea and diarrhea and the churning of the stomach, migraine wasn't big of a deal and I finally went without taking coffee. This is really a miracle drug for Diabetes. Thank you."

10 / 10
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  • FatTim
  • Taken for 1 to 6 months
  • March 27, 2021

Rybelsus (semaglutide) "My A1c has been hovering around 7 and my weight was creeping up so my doc suggested this. I started on the 3 and the nausea and projectile vomiting was rough...indeed I didn’t think I could handle it. Then I discovered if I take it when I wake in the small hours to pee if I took it then I had almost no problems. I’m now up to the 15mg dose and so far I’ve gone from around 255lb to about 220lb and falling. Two whole jean sizes...haven’t done new labs yet...but the weight loss is remarkable...it’s also quite weird to essentially almost never feel hungry anymore"

8 / 10
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  • Annie...
  • Taken for 6 months to 1 year
  • September 9, 2019

Ozempic (semaglutide) "Hi! Have been on Ozempic for 10 months. The first 3 months were very difficult with strong side effects. Mainly constant, but low level, nausea, occasional vomiting, and diarrhea (especially two days after the injection). However around month 3 the nausea and diarrhea subsided greatly and my appetite returned. I had lost weight very quickly (42 lbs in 3 months due to not really eating much). Had to take supplements for a while but am now eating well. The rapid weight loss led to telogen effluvium, a temporary hair loss condition. (I shed A LOT but never showed any baldness or anything). Currently, my weight is still down (I was taken off my blood pressure medication!), my blood counts are perfect, my hair is getting thick, and I eat normally. I now experience virtually no side effects. Really, really, glad I stuck out the side effects at the beginning."

7 / 10
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  • starr...
  • March 13, 2023

Rybelsus (semaglutide) "Started the 3mg for one month and lost 7lbs. I read the reviews about the side effects and saw most have little side effects if taken early, so I take it around 5/6 am with little water. By the time I'm ready to get going for the day, I can have a cup of tea, as it says not to drink within the hour of taking it. My appetite has decreased, I don't pick/ snack and my portion size has decreased. I only ever feel nauseous if I eat too much, but I've got to grips with how much I can eat and to be honest, I don't really feel hungry. I was eating because I felt I should. No other side effects. On my second month so will see how it goes."

8 / 10
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  • Jan
  • March 26, 2021

Rybelsus (semaglutide) "I started on Rybelsus and only took 4 doses. I didn’t get terrible stomach upset but my abdomen went completely numb. I’ve been off of the medication for 4 days and am still completely numb. Went to ER and they ran blood work and CAT scan, all was normal. I went to chiropractor and again all was normal. Numbness is listed as rare side effect on drugs.com website which my chiropractor looked up. My endocrinologist isn’t helpful, and I called Rybelsus and they were less than helpful. I’ve now spent hundreds of dollars. I’m very concerned and praying this goes away. I am so numb it hurts to touch my skin. Beware of this medication!"

1 / 10
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  • Bears...
  • Taken for 1 to 6 months
  • January 7, 2021

Ozempic (semaglutide) "I have been on Ozempic for 6 months now. After the first few injections, I was so sick vomiting and diarrhea all the time. I called the doc and said I couldn’t take this anymore. Of course I lost weight, as I couldn’t keep anything in me. I researched the medication itself to understand exactly what it was & how it worked. I decided to stay on it. My A1c was 8.8 when I started. 3 months later, 6.4. I am down 36 pounds. I have been exercising regularly for 3 months now, running 3.5 miles 5 X a week. The confidence and energy from the weight loss outweighs all the negative side affects in the beginning for me! Blood sugar control is excellent, and I suspect will only improve after the continued weight loss. I have stalled with weight loss twice now, but not giving up, and sticking to my exercise (changing it up a bit to gain more muscle to burn fat), I have been able to overcome the stalls and continue to lose. Complete game changer medication for me!!"

8 / 10
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  • Stella
  • Taken for 1 to 6 months
  • October 12, 2020

Ozempic (semaglutide) "Used Ozempic for 2 months, had to stop taking it. I had themost toxic reaction(s) from any prescription drug I have ever taken. Terrible chemical smelling burps, felt sick often, caused serious bowel problems. Will never take this drug again, benefits are not worth the grief."

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  • Dannie
  • Taken for 1 to 6 months
  • March 24, 2019

Ozempic (semaglutide) "I’ve been on this med for 7 weeks. I’ve lost 25 lbs and my daily blood sugars range from 60 - 90. I use it along with 500 mg Metformin. The first couple of weeks were hard with nausea and stomach cramps. I also had the headaches that others have mentioned in the first couple of days. In week 3, I increased from 0.25 to 0.50. Then came the diarrhea. It wasn't too bad; I was just happy that I could go. I’m now taking 1.0 and experiencing sulfuric burping. Ugh! After doing some research on home remedies to help with the burping, I’m trying a spoon of apple cider vinegar. If you can make it through the first few weeks and you can be somewhat disciplined, you will notice a huge difference in how you feel. In my opinion, the side effects are manageable when I compare the weight gain while taking Insulin. BTW - I’m not severely obese. Prior to being on this drug, my weight was 205, and I’m 5’9 and 47 years old. I hope this is helpful to someone."

9 / 10
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  • Cin...
  • July 12, 2019

Ozempic (semaglutide) "Well, so far and this is my 3rd week (I'm taking it for weight loss only) and I'm a little sick in my stomach, but no throwing up or bad gas. Fingers crossed, I hope I don't. Some of these side effects sound awful. I've lost about 2 pounds a week so far, and if this keeps up, I am going all the way with this. I take 0.25 so far. My doctor wanted me to try because I've lost 275 pounds all by myself, and I've been at a standstill. He wants me to get over this hump, so I'm trying this and so far so good. I hope it continues to be good for me. I hate it's not for some... And by the way, I've never had diabetes. So I'm taking it only for weight issues. I'm 50, and it's taken me 4 years to lose the 275lb."

8 / 10
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  • Wonde...
  • Taken for 6 months to 1 year
  • September 9, 2022

Rybelsus (semaglutide) "Was placed on this medication to help with PCOS caused insulin resistance and obesity. The first two months were a bit uncomfortable - I was nauseated a lot and had bouts of constipation and diarrhea. Fortunately, immediately starting it, my sugar cravings disappeared. I think I had a rough couple of months because of my old eating habits since this medicine slows how fast your stomach empties. As I developed better eating habits this has gone away completely. I’ve been on this for almost a year now and have lost almost 60lbs. I’m about 5 lbs away from being a normal weight and I’m barely making any effort at this point; the weight is just coming off. I feel the healthiest I’ve felt in over a decade and have been seeing my PCOS symptoms reduce as the weight comes off. This medicine was a miracle for me. I’ve struggled for a decade trying to get my weight under control. Once the insulin resistance was resolved, it literally fell off."

10 / 10
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  • Los
  • March 3, 2020

Ozempic (semaglutide) "I have taken ozempic for four days and have not experienced any of the symptoms others are saying they have had with one exception: I am very tired. I am eating a little less but do not feel like some say they can't eat at all. My bs is down to 110 and I have lost three pounds. So far I see only good things. I hope it stays that way as I want to lose about 30 pounds and not take metformin. Hopeful!!!!"

10 / 10
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  • Nay
  • November 2, 2019

Ozempic (semaglutide) "I have been on ozempic for 13 weeks, I started out on .25 mg for 4 weeks then moved up to .5 mg for 2 weeks and then to the 1 mg. My A1C was 10.9 when I started the injection and after 12 weeks my A1C was 7.6 and I have lost 34lbs! I am feeling great and I continue to lose weight. I am so thankful for this injection!"

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • May 10, 2024

Ozempic (semaglutide) "This medication is working well for me. My blood sugar at last testing was 6.7 from a long-term level of 7.7+. I am down around 50 pounds since I started taking it. I have had problems adjusting to it. I easily go whole days without eating. I sometimes have to force myself to eat. That is sometimes a task. I feel bloated a lot. The smell of food makes me nauseous. Spoonfuls of food make me want to push the plate away. I did have a problem 6 months ago where I went nearly a week without eating. I passed out in my kitchen from dehydration, landed on my face breaking several teeth, and was hospitalized for 5 days. This was after getting my Ozempic switched from 0.5mg to 1mg. I haven't had that kind of problem after moving back to 0.5mg, but not eating at all for 1-2 days is still an issue. I continue to take it because my blood sugar is where I would like it to be and my weight is way down."

8 / 10
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  • MKano
  • Taken for 1 to 6 months
  • January 6, 2020

Ozempic (semaglutide) "Have been on Ozempic for 3 months. Minimal side effects. With a diet change (no more chips, booze, and candy) and exercise, I was able to reduce me A1C from 11 to 5.8. I lost 70 pounds. Ever since Ozempic, I find it keeps my sugar consistent at 110 or under, even on cheat days. Mild stomach pain. It has reduce my hunger as others commented. While I am responsible for much of weight loss, the Ozempic had a strong role in it as well."

10 / 10
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  • Rose
  • Taken for 1 to 6 months
  • February 25, 2020

Ozempic (semaglutide) "This medicine did what it was supposed to. It lowered my A1C, but it also almost me off. I was so sick. I had to stop it. The worst medicine ever! I felt like I was reaching the end of my life. I couldn't do anything, couldn't eat, couldn't even get out of bed. I lost a lot of weight! My stomach hurt, my side hurt, my back hurt. I started feeling better once I quit taking it! I will never take it again! It almost felt like it was poisoning my entire body!"

1 / 10
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  • Fife...
  • Taken for less than 1 month
  • August 29, 2021

Ozempic (semaglutide) "On week 4 now, honestly the first 2 weeks were a nightmare, doctors don’t tell you “stay away from fatty foods and don’t over eat” if they did I wouldn’t have had the most horrible sulphur burps that made my eyes water , projectile vomiting, diarrhoea and stomach pain not to mention constant nausea even during night , I finally figured out not to eat too much and avoid fatty foods completely!! This was a game changer and now I’m doing ok, lost 21 pounds so far which is mad but mostly because in 2 weeks I’ve eaten probably 4000 calories. I’m back to wanting to eat again but have to control myself or face the terrible consequences. Blood sugars are all over the place as you can imagine however insulin sensitivity is way better. Just takes time to get used to, hope this helps"

6 / 10
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  • Retired...
  • Taken for 1 to 6 months
  • February 25, 2020

Ozempic (semaglutide) "Take my comments for what they are worth since I changed many things in my life at the same time...but.. I think Ozempic is great. After 5 months reduced my A1c from 9.7 to 5.9. Lost almost 25 pounds. Am at .5mg and it has drastically reduced my appetite. Between smaller stomach and this drug often push my plate away before finishing, rarely desire for dessert. Little to no side effects overall. Some stomach issues like constipation, bloating but can’t rule out dietary changes being the cause also. Went on a low carb diet and really stuck to it for once and increased exercise a lot. Use of the Freestyle Libre Sensor really really helped too! Being able to learn how things effect your blood sugar in real time is a great motivator to do the right thing, combine carbs with protein etc Hoping to lower other meds I am on when I see my Doctor next month. Once a week tiny needle (virtually pain free) is a far better system than pills everyday."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.